RBE and related modeling in carbon-ion therapy
نویسندگان
چکیده
منابع مشابه
RBE and related modeling in carbon-ion therapy.
Carbon ion therapy is a promising evolving modality in radiotherapy to treat tumors that are radioresistant against photon treatments. As carbon ions are more effective in normal and tumor tissue, the relative biological effectiveness (RBE) has to be calculated by bio-mathematical models and has to be considered in the dose prescription. This review (i) introduces the concept of the RBE and its...
متن کاملMapping of RBE-weighted doses between HIMAC- and LEM-Based treatment planning systems for carbon ion therapy.
PURPOSE A method was developed to convert clinically prescribed RBE (Relative Biological Effectiveness)-weighted doses from the approach used at the Heavy-Ion Medical Accelerator (HIMAC) at the National Institute of Radiological Science, Chiba, Japan, to the LEM (Local Effect Model)-based TReatment planning for Particles (TRiP98) approach used in the pilot project at the GSI Helmholtzzentrum, D...
متن کاملPreliminary calculation of RBE-weighted dose distribution for cerebral radionecrosis in carbon-ion treatment planning.
Cerebral radionecrosis is a significant side effect in radiotherapy for brain cancer. The purpose of this study is to calculate the relative biological effectiveness (RBE) of carbon-ion beams on brain cells and to show RBE-weighted dose distributions for cerebral radionecrosis speculation in a carbon-ion treatment planning system. The RBE value of the radionecrosis for the carbon-ion beam is ca...
متن کاملImpact of Various Beam Parameters on Lateral Scattering in Proton and Carbon-ion Therapy
Background: In radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. Heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness.Methods: In this study, we used Monte Carlo method-based Geant4 toolkit to s...
متن کاملCarbon ion therapy to debut in Europe.
fter 14 years of construction, the Large Hadron Collider, the world’s largest particle accelerator, fired its first beam of protons in September from its home at the European Organization for Nuclear Research (CERN) near Geneva. Now a spinoff technology for treating cancer is also nearing its European debut. The first European center to offer carbon ion therapy — a type of radiation treatment t...
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ژورنال
عنوان ژورنال: Physics in Medicine & Biology
سال: 2017
ISSN: 1361-6560
DOI: 10.1088/1361-6560/aa9102